Pease has an MFA from the University of Pennsylvania and a BFA from Indiana University. He also studied as an exchange scholar at the Royal Academy of Art London. Mark has taught at the School of Design, University of Pennsylvania, the College of Visual Art and Design, University of North Texas, and Northwestern University in Saint Paul, Minnesota. He currently works at Southern Illinois University and teaches courses in computer graphics, digital animation, video art, and 3D modeling. He has shown in national and international exhibitions, including the Los Angeles Center for Digital Art, the Elmhurst Art Museum, the Contemporary Art Museum St. Louis, the International Print Center New York, and the Soap Factory.